Cocodiazine
Brand names,
Cocodiazine
Analogs
Cocodiazine
Brand Names Mixture
Cocodiazine
Chemical_Formula
C10H10N4O2S
Cocodiazine
RX_link
http://www.rxlist.com/cgi/generic3/silversulf.htm
Cocodiazine
fda sheet
Cocodiazine
msds (material safety sheet)
Cocodiazine
Synthesis Reference
No information avaliable
Cocodiazine
Molecular Weight
250.278 g/mol
Cocodiazine
Melting Point
No information avaliable
Cocodiazine
H2O Solubility
No information avaliable
Cocodiazine
State
Solid
Cocodiazine
LogP
1.883
Cocodiazine
Dosage Forms
Cream
Cocodiazine
Indication
For the treatment of rheumatic fever and meningococcal meningitis
Cocodiazine
Pharmacology
Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Cocodiazine
Absorption
No information avaliable
Cocodiazine
side effects and Toxicity
No information avaliable
Cocodiazine
Patient Information
No information avaliable
Cocodiazine
Organisms Affected
Enteric bacteria and other eubacteria