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Sulfapyrimidine Brand names, Sulfapyrimidine Analogs

Sulfapyrimidine Brand Names Mixture

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Sulfapyrimidine Chemical_Formula


Sulfapyrimidine RX_link

Sulfapyrimidine fda sheet

Sulfapyrimidine msds (material safety sheet)

Sulfapyrimidine Synthesis Reference

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Sulfapyrimidine Molecular Weight

250.278 g/mol

Sulfapyrimidine Melting Point

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Sulfapyrimidine H2O Solubility

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Sulfapyrimidine State


Sulfapyrimidine LogP


Sulfapyrimidine Dosage Forms


Sulfapyrimidine Indication

For the treatment of rheumatic fever and meningococcal meningitis

Sulfapyrimidine Pharmacology

Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulfapyrimidine Absorption

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Sulfapyrimidine side effects and Toxicity

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Sulfapyrimidine Patient Information

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Sulfapyrimidine Organisms Affected

Enteric bacteria and other eubacteria