Microsulfon
Brand names,
Microsulfon
Analogs
Microsulfon
Brand Names Mixture
Microsulfon
Chemical_Formula
C10H10N4O2S
Microsulfon
RX_link
http://www.rxlist.com/cgi/generic3/silversulf.htm
Microsulfon
fda sheet
Microsulfon
msds (material safety sheet)
Microsulfon
Synthesis Reference
No information avaliable
Microsulfon
Molecular Weight
250.278 g/mol
Microsulfon
Melting Point
No information avaliable
Microsulfon
H2O Solubility
No information avaliable
Microsulfon
State
Solid
Microsulfon
LogP
1.883
Microsulfon
Dosage Forms
Cream
Microsulfon
Indication
For the treatment of rheumatic fever and meningococcal meningitis
Microsulfon
Pharmacology
Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Microsulfon
Absorption
No information avaliable
Microsulfon
side effects and Toxicity
No information avaliable
Microsulfon
Patient Information
No information avaliable
Microsulfon
Organisms Affected
Enteric bacteria and other eubacteria