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Adiazine Brand names, Adiazine Analogs

Adiazine Brand Names Mixture

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Adiazine Chemical_Formula


Adiazine RX_link

Adiazine fda sheet

Adiazine msds (material safety sheet)

Adiazine Synthesis Reference

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Adiazine Molecular Weight

250.278 g/mol

Adiazine Melting Point

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Adiazine H2O Solubility

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Adiazine State


Adiazine LogP


Adiazine Dosage Forms


Adiazine Indication

For the treatment of rheumatic fever and meningococcal meningitis

Adiazine Pharmacology

Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Adiazine Absorption

No information avaliable

Adiazine side effects and Toxicity

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Adiazine Patient Information

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Adiazine Organisms Affected

Enteric bacteria and other eubacteria