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Thermazene Brand names, Thermazene Analogs

Thermazene Brand Names Mixture

  • No information avaliable

Thermazene Chemical_Formula

C10H10N4O2S

Thermazene RX_link

http://www.rxlist.com/cgi/generic3/silversulf.htm

Thermazene fda sheet

Thermazene msds (material safety sheet)

Thermazene Synthesis Reference

No information avaliable

Thermazene Molecular Weight

250.278 g/mol

Thermazene Melting Point

No information avaliable

Thermazene H2O Solubility

No information avaliable

Thermazene State

Solid

Thermazene LogP

1.883

Thermazene Dosage Forms

Cream

Thermazene Indication

For the treatment of rheumatic fever and meningococcal meningitis

Thermazene Pharmacology

Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Thermazene Absorption

No information avaliable

Thermazene side effects and Toxicity

No information avaliable

Thermazene Patient Information

No information avaliable

Thermazene Organisms Affected

Enteric bacteria and other eubacteria