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Spofadrizine Brand names, Spofadrizine Analogs

Spofadrizine Brand Names Mixture

  • No information avaliable

Spofadrizine Chemical_Formula


Spofadrizine RX_link


Spofadrizine fda sheet

Spofadrizine msds (material safety sheet)

Spofadrizine Synthesis Reference

No information avaliable

Spofadrizine Molecular Weight

250.278 g/mol

Spofadrizine Melting Point

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Spofadrizine H2O Solubility

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Spofadrizine State


Spofadrizine LogP


Spofadrizine Dosage Forms


Spofadrizine Indication

For the treatment of rheumatic fever and meningococcal meningitis

Spofadrizine Pharmacology

Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Spofadrizine Absorption

No information avaliable

Spofadrizine side effects and Toxicity

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Spofadrizine Patient Information

No information avaliable

Spofadrizine Organisms Affected

Enteric bacteria and other eubacteria