Sulfonsol
Brand names,
Sulfonsol
Analogs
Sulfonsol
Brand Names Mixture
Sulfonsol
Chemical_Formula
C10H10N4O2S
Sulfonsol
RX_link
http://www.rxlist.com/cgi/generic3/silversulf.htm
Sulfonsol
fda sheet
Sulfonsol
msds (material safety sheet)
Sulfonsol
Synthesis Reference
No information avaliable
Sulfonsol
Molecular Weight
250.278 g/mol
Sulfonsol
Melting Point
No information avaliable
Sulfonsol
H2O Solubility
No information avaliable
Sulfonsol
State
Solid
Sulfonsol
LogP
1.883
Sulfonsol
Dosage Forms
Cream
Sulfonsol
Indication
For the treatment of rheumatic fever and meningococcal meningitis
Sulfonsol
Pharmacology
Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulfonsol
Absorption
No information avaliable
Sulfonsol
side effects and Toxicity
No information avaliable
Sulfonsol
Patient Information
No information avaliable
Sulfonsol
Organisms Affected
Enteric bacteria and other eubacteria