Sulfapirimidin
Brand names,
Sulfapirimidin
Analogs
Sulfapirimidin
Brand Names Mixture
Sulfapirimidin
Chemical_Formula
C10H10N4O2S
Sulfapirimidin
RX_link
http://www.rxlist.com/cgi/generic3/silversulf.htm
Sulfapirimidin
fda sheet
Sulfapirimidin
msds (material safety sheet)
Sulfapirimidin
Synthesis Reference
No information avaliable
Sulfapirimidin
Molecular Weight
250.278 g/mol
Sulfapirimidin
Melting Point
No information avaliable
Sulfapirimidin
H2O Solubility
No information avaliable
Sulfapirimidin
State
Solid
Sulfapirimidin
LogP
1.883
Sulfapirimidin
Dosage Forms
Cream
Sulfapirimidin
Indication
For the treatment of rheumatic fever and meningococcal meningitis
Sulfapirimidin
Pharmacology
Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulfapirimidin
Absorption
No information avaliable
Sulfapirimidin
side effects and Toxicity
No information avaliable
Sulfapirimidin
Patient Information
No information avaliable
Sulfapirimidin
Organisms Affected
Enteric bacteria and other eubacteria