Sildaflo
Brand names,
Sildaflo
Analogs
Sildaflo
Brand Names Mixture
Sildaflo
Chemical_Formula
C10H10N4O2S
Sildaflo
RX_link
http://www.rxlist.com/cgi/generic3/silversulf.htm
Sildaflo
fda sheet
Sildaflo
msds (material safety sheet)
Sildaflo
Synthesis Reference
No information avaliable
Sildaflo
Molecular Weight
250.278 g/mol
Sildaflo
Melting Point
No information avaliable
Sildaflo
H2O Solubility
No information avaliable
Sildaflo
State
Solid
Sildaflo
LogP
1.883
Sildaflo
Dosage Forms
Cream
Sildaflo
Indication
For the treatment of rheumatic fever and meningococcal meningitis
Sildaflo
Pharmacology
Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sildaflo
Absorption
No information avaliable
Sildaflo
side effects and Toxicity
No information avaliable
Sildaflo
Patient Information
No information avaliable
Sildaflo
Organisms Affected
Enteric bacteria and other eubacteria