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Trifonamide Brand names, Trifonamide Analogs

Trifonamide Brand Names Mixture

  • No information avaliable

Trifonamide Chemical_Formula


Trifonamide RX_link

Trifonamide fda sheet

Trifonamide msds (material safety sheet)

Trifonamide Synthesis Reference

No information avaliable

Trifonamide Molecular Weight

250.278 g/mol

Trifonamide Melting Point

No information avaliable

Trifonamide H2O Solubility

No information avaliable

Trifonamide State


Trifonamide LogP


Trifonamide Dosage Forms


Trifonamide Indication

For the treatment of rheumatic fever and meningococcal meningitis

Trifonamide Pharmacology

Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Trifonamide Absorption

No information avaliable

Trifonamide side effects and Toxicity

No information avaliable

Trifonamide Patient Information

No information avaliable

Trifonamide Organisms Affected

Enteric bacteria and other eubacteria