Sulfose
Brand names,
Sulfose
Analogs
Sulfose
Brand Names Mixture
Sulfose
Chemical_Formula
C10H10N4O2S
Sulfose
RX_link
http://www.rxlist.com/cgi/generic3/silversulf.htm
Sulfose
fda sheet
Sulfose
msds (material safety sheet)
Sulfose
Synthesis Reference
No information avaliable
Sulfose
Molecular Weight
250.278 g/mol
Sulfose
Melting Point
No information avaliable
Sulfose
H2O Solubility
No information avaliable
Sulfose
State
Solid
Sulfose
LogP
1.883
Sulfose
Dosage Forms
Cream
Sulfose
Indication
For the treatment of rheumatic fever and meningococcal meningitis
Sulfose
Pharmacology
Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulfose
Absorption
No information avaliable
Sulfose
side effects and Toxicity
No information avaliable
Sulfose
Patient Information
No information avaliable
Sulfose
Organisms Affected
Enteric bacteria and other eubacteria