Piridisir
Brand names,
Piridisir
Analogs
Piridisir
Brand Names Mixture
Piridisir
Chemical_Formula
C10H10N4O2S
Piridisir
RX_link
http://www.rxlist.com/cgi/generic3/silversulf.htm
Piridisir
fda sheet
Piridisir
msds (material safety sheet)
Piridisir
Synthesis Reference
No information avaliable
Piridisir
Molecular Weight
250.278 g/mol
Piridisir
Melting Point
No information avaliable
Piridisir
H2O Solubility
No information avaliable
Piridisir
State
Solid
Piridisir
LogP
1.883
Piridisir
Dosage Forms
Cream
Piridisir
Indication
For the treatment of rheumatic fever and meningococcal meningitis
Piridisir
Pharmacology
Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Piridisir
Absorption
No information avaliable
Piridisir
side effects and Toxicity
No information avaliable
Piridisir
Patient Information
No information avaliable
Piridisir
Organisms Affected
Enteric bacteria and other eubacteria