Sulfanil
Brand names,
Sulfanil
Analogs
Sulfanil
Brand Names Mixture
Sulfanil
Chemical_Formula
C10H10N4O2S
Sulfanil
RX_link
http://www.rxlist.com/cgi/generic3/silversulf.htm
Sulfanil
fda sheet
Sulfanil
msds (material safety sheet)
Sulfanil
Synthesis Reference
No information avaliable
Sulfanil
Molecular Weight
250.278 g/mol
Sulfanil
Melting Point
No information avaliable
Sulfanil
H2O Solubility
No information avaliable
Sulfanil
State
Solid
Sulfanil
LogP
1.883
Sulfanil
Dosage Forms
Cream
Sulfanil
Indication
For the treatment of rheumatic fever and meningococcal meningitis
Sulfanil
Pharmacology
Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulfanil
Absorption
No information avaliable
Sulfanil
side effects and Toxicity
No information avaliable
Sulfanil
Patient Information
No information avaliable
Sulfanil
Organisms Affected
Enteric bacteria and other eubacteria