Doxycin
Brand names,
Doxycin
Analogs
Doxycin
Brand Names Mixture
Doxycin
Chemical_Formula
C22H24N2O8
Doxycin
RX_link
http://www.rxlist.com/cgi/generic/doxycyc.htm
Doxycin
fda sheet
Doxycin
msds (material safety sheet)
Doxycin
Synthesis Reference
C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)
Doxycin
Molecular Weight
444.435 g/mol
Doxycin
Melting Point
201 oC
Doxycin
H2O Solubility
630 mg/L
Doxycin
State
Solid
Doxycin
LogP
-1.219
Doxycin
Dosage Forms
Tablet; Capsule; Gel; Liquid; Powder; Powder for solution
Doxycin
Indication
For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve
Doxycin
Pharmacology
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.
Doxycin
Absorption
completely absorbed after oral administration
Doxycin
side effects and Toxicity
anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)
Doxycin
Patient Information
Doxycin
Organisms Affected
Enteric bacteria and other eubacteria