Atridox
Brand names,
Atridox
Analogs
Atridox
Brand Names Mixture
Atridox
Chemical_Formula
C22H24N2O8
Atridox
RX_link
http://www.rxlist.com/cgi/generic/doxycyc.htm
Atridox
fda sheet
Atridox
msds (material safety sheet)
Atridox
Synthesis Reference
C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)
Atridox
Molecular Weight
444.435 g/mol
Atridox
Melting Point
201 oC
Atridox
H2O Solubility
630 mg/L
Atridox
State
Solid
Atridox
LogP
-1.219
Atridox
Dosage Forms
Tablet; Capsule; Gel; Liquid; Powder; Powder for solution
Atridox
Indication
For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve
Atridox
Pharmacology
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.
Atridox
Absorption
completely absorbed after oral administration
Atridox
side effects and Toxicity
anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)
Atridox
Patient Information
Atridox
Organisms Affected
Enteric bacteria and other eubacteria