Doxy-Caps
Brand names,
Doxy-Caps
Analogs
Doxy-Caps
Brand Names Mixture
Doxy-Caps
Chemical_Formula
C22H24N2O8
Doxy-Caps
RX_link
http://www.rxlist.com/cgi/generic/doxycyc.htm
Doxy-Caps
fda sheet
Doxy-Caps
msds (material safety sheet)
Doxy-Caps
Synthesis Reference
C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)
Doxy-Caps
Molecular Weight
444.435 g/mol
Doxy-Caps
Melting Point
201 oC
Doxy-Caps
H2O Solubility
630 mg/L
Doxy-Caps
State
Solid
Doxy-Caps
LogP
-1.219
Doxy-Caps
Dosage Forms
Tablet; Capsule; Gel; Liquid; Powder; Powder for solution
Doxy-Caps
Indication
For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve
Doxy-Caps
Pharmacology
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.
Doxy-Caps
Absorption
completely absorbed after oral administration
Doxy-Caps
side effects and Toxicity
anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)
Doxy-Caps
Patient Information
Doxy-Caps
Organisms Affected
Enteric bacteria and other eubacteria