Doryx
Doryx Brand names, Doryx Analogs
Doryx Brand Names Mixture
- No information avaliable
Doryx Chemical_Formula
C22H24N2O8
Doryx RX_link
http://www.rxlist.com/cgi/generic/doxycyc.htm
Doryx fda sheet
Doryx msds (material safety sheet)
Doryx Synthesis Reference
C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)
Doryx Molecular Weight
444.435 g/mol
Doryx Melting Point
201 oC
Doryx H2O Solubility
630 mg/L
Doryx State
Solid
Doryx LogP
-1.219
Doryx Dosage Forms
Tablet; Capsule; Gel; Liquid; Powder; Powder for solution
Doryx Indication
For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve
Doryx Pharmacology
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.
Doryx Absorption
completely absorbed after oral administration
Doryx side effects and Toxicity
anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)
Doryx Patient Information
Doryx Organisms Affected
Enteric bacteria and other eubacteria
