Doxylin
Doxylin Brand names, Doxylin Analogs
Doxylin Brand Names Mixture
- No information avaliable
Doxylin Chemical_Formula
C22H24N2O8
Doxylin RX_link
http://www.rxlist.com/cgi/generic/doxycyc.htm
Doxylin fda sheet
Doxylin msds (material safety sheet)
Doxylin Synthesis Reference
C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)
Doxylin Molecular Weight
444.435 g/mol
Doxylin Melting Point
201 oC
Doxylin H2O Solubility
630 mg/L
Doxylin State
Solid
Doxylin LogP
-1.219
Doxylin Dosage Forms
Tablet; Capsule; Gel; Liquid; Powder; Powder for solution
Doxylin Indication
For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve
Doxylin Pharmacology
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.
Doxylin Absorption
completely absorbed after oral administration
Doxylin side effects and Toxicity
anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)
Doxylin Patient Information
Doxylin Organisms Affected
Enteric bacteria and other eubacteria
