Monodox
Monodox Brand names, Monodox Analogs
Monodox Brand Names Mixture
- No information avaliable
Monodox Chemical_Formula
C22H24N2O8
Monodox RX_link
http://www.rxlist.com/cgi/generic/doxycyc.htm
Monodox fda sheet
Monodox msds (material safety sheet)
Monodox Synthesis Reference
C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)
Monodox Molecular Weight
444.435 g/mol
Monodox Melting Point
201 oC
Monodox H2O Solubility
630 mg/L
Monodox State
Solid
Monodox LogP
-1.219
Monodox Dosage Forms
Tablet; Capsule; Gel; Liquid; Powder; Powder for solution
Monodox Indication
For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve
Monodox Pharmacology
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.
Monodox Absorption
completely absorbed after oral administration
Monodox side effects and Toxicity
anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)
Monodox Patient Information
Monodox Organisms Affected
Enteric bacteria and other eubacteria
