Doxytetracycline
Doxytetracycline Brand names, Doxytetracycline Analogs
Doxytetracycline Brand Names Mixture
- No information avaliable
Doxytetracycline Chemical_Formula
C22H24N2O8
Doxytetracycline RX_link
http://www.rxlist.com/cgi/generic/doxycyc.htm
Doxytetracycline fda sheet
Doxytetracycline msds (material safety sheet)
Doxytetracycline Synthesis Reference
C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)
Doxytetracycline Molecular Weight
444.435 g/mol
Doxytetracycline Melting Point
201 oC
Doxytetracycline H2O Solubility
630 mg/L
Doxytetracycline State
Solid
Doxytetracycline LogP
-1.219
Doxytetracycline Dosage Forms
Tablet; Capsule; Gel; Liquid; Powder; Powder for solution
Doxytetracycline Indication
For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve
Doxytetracycline Pharmacology
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.
Doxytetracycline Absorption
completely absorbed after oral administration
Doxytetracycline side effects and Toxicity
anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)
Doxytetracycline Patient Information
Doxytetracycline Organisms Affected
Enteric bacteria and other eubacteria
