Nu-Doxycycline
Brand names,
Nu-Doxycycline
Analogs
Nu-Doxycycline
Brand Names Mixture
Nu-Doxycycline
Chemical_Formula
C22H24N2O8
Nu-Doxycycline
RX_link
http://www.rxlist.com/cgi/generic/doxycyc.htm
Nu-Doxycycline
fda sheet
Nu-Doxycycline
msds (material safety sheet)
Nu-Doxycycline
Synthesis Reference
C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)
Nu-Doxycycline
Molecular Weight
444.435 g/mol
Nu-Doxycycline
Melting Point
201 oC
Nu-Doxycycline
H2O Solubility
630 mg/L
Nu-Doxycycline
State
Solid
Nu-Doxycycline
LogP
-1.219
Nu-Doxycycline
Dosage Forms
Tablet; Capsule; Gel; Liquid; Powder; Powder for solution
Nu-Doxycycline
Indication
For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve
Nu-Doxycycline
Pharmacology
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.
Nu-Doxycycline
Absorption
completely absorbed after oral administration
Nu-Doxycycline
side effects and Toxicity
anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)
Nu-Doxycycline
Patient Information
Nu-Doxycycline
Organisms Affected
Enteric bacteria and other eubacteria