Doxy-Lemmon
Brand names,
Doxy-Lemmon
Analogs
Doxy-Lemmon
Brand Names Mixture
Doxy-Lemmon
Chemical_Formula
C22H24N2O8
Doxy-Lemmon
RX_link
http://www.rxlist.com/cgi/generic/doxycyc.htm
Doxy-Lemmon
fda sheet
Doxy-Lemmon
msds (material safety sheet)
Doxy-Lemmon
Synthesis Reference
C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)
Doxy-Lemmon
Molecular Weight
444.435 g/mol
Doxy-Lemmon
Melting Point
201 oC
Doxy-Lemmon
H2O Solubility
630 mg/L
Doxy-Lemmon
State
Solid
Doxy-Lemmon
LogP
-1.219
Doxy-Lemmon
Dosage Forms
Tablet; Capsule; Gel; Liquid; Powder; Powder for solution
Doxy-Lemmon
Indication
For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve
Doxy-Lemmon
Pharmacology
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.
Doxy-Lemmon
Absorption
completely absorbed after oral administration
Doxy-Lemmon
side effects and Toxicity
anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)
Doxy-Lemmon
Patient Information
Doxy-Lemmon
Organisms Affected
Enteric bacteria and other eubacteria