Periostat
Periostat Brand names, Periostat Analogs
Periostat Brand Names Mixture
- No information avaliable
Periostat Chemical_Formula
C22H24N2O8
Periostat RX_link
http://www.rxlist.com/cgi/generic/doxycyc.htm
Periostat fda sheet
Periostat msds (material safety sheet)
Periostat Synthesis Reference
C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)
Periostat Molecular Weight
444.435 g/mol
Periostat Melting Point
201 oC
Periostat H2O Solubility
630 mg/L
Periostat State
Solid
Periostat LogP
-1.219
Periostat Dosage Forms
Tablet; Capsule; Gel; Liquid; Powder; Powder for solution
Periostat Indication
For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve
Periostat Pharmacology
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.
Periostat Absorption
completely absorbed after oral administration
Periostat side effects and Toxicity
anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)
Periostat Patient Information
Periostat Organisms Affected
Enteric bacteria and other eubacteria
