DEB en es it fr

DEB Brand names, DEB Analogs

DEB Brand Names Mixture

  • No information avaliable

DEB Chemical_Formula


DEB RX_link

DEB fda sheet

DEB msds (material safety sheet)

DEB Synthesis Reference

No information avaliable

DEB Molecular Weight

250.278 g/mol

DEB Melting Point

No information avaliable

DEB H2O Solubility

No information avaliable

DEB State




DEB Dosage Forms


DEB Indication

For the treatment of rheumatic fever and meningococcal meningitis

DEB Pharmacology

Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

DEB Absorption

No information avaliable

DEB side effects and Toxicity

No information avaliable

DEB Patient Information

No information avaliable

DEB Organisms Affected

Enteric bacteria and other eubacteria