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AMPH-B Brand names, AMPH-B Analogs

AMPH-B Brand Names Mixture

  • No information avaliable

AMPH-B Chemical_Formula


AMPH-B RX_link

AMPH-B fda sheet


AMPH-B msds (material safety sheet)


AMPH-B Synthesis Reference

No information avaliable

AMPH-B Molecular Weight

924.079 g/mol

AMPH-B Melting Point

170.0 oC

AMPH-B H2O Solubility

750 mg/L

AMPH-B State




AMPH-B Dosage Forms

Slow intravenous-infusion

AMPH-B Indication

Used to treat potentially life threatening fungal infections.

AMPH-B Pharmacology

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

AMPH-B Absorption

Bioavailability is 100% for intravenous infusion.

AMPH-B side effects and Toxicity

Oral, rat: LD50 = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

AMPH-B Patient Information

No information avaliable

AMPH-B Organisms Affected

Various Fungus Species