Abelcet
Abelcet Brand names, Abelcet Analogs
Abelcet Brand Names Mixture
- No information avaliable
Abelcet Chemical_Formula
C47H73NO17
Abelcet RX_link
http://www.rxlist.com/cgi/generic2/amphoter.htm
Abelcet fda sheet
Abelcet msds (material safety sheet)
Abelcet Synthesis Reference
No information avaliable
Abelcet Molecular Weight
924.079 g/mol
Abelcet Melting Point
170.0 oC
Abelcet H2O Solubility
750 mg/L
Abelcet State
Solid
Abelcet LogP
0.947
Abelcet Dosage Forms
Slow intravenous-infusion
Abelcet Indication
Used to treat potentially life threatening fungal infections.
Abelcet Pharmacology
Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.
Abelcet Absorption
Bioavailability is 100% for intravenous infusion.
Abelcet side effects and Toxicity
Oral, rat: LD50 = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.
Abelcet Patient Information
No information avaliable
Abelcet Organisms Affected
Various Fungus Species
