Fungizone

Fungizone Brand names, Fungizone Analogs

Fungizone Brand Names Mixture

No information avaliable

Fungizone Chemical_Formula

C₄₇H₇₃NO₁₇

Fungizone RX_link

http://www.rxlist.com/cgi/generic2/amphoter.htm

Fungizone fda sheet

Fungizone FDA

Fungizone msds (material safety sheet)

Fungizone MSDS

Fungizone Synthesis Reference

No information avaliable

Fungizone Molecular Weight

924.079 g/mol

Fungizone Melting Point

170.0 ^oC

Fungizone H₂O Solubility

750 mg/L

Fungizone State

Solid

Fungizone LogP

0.947

Fungizone Dosage Forms

Slow intravenous-infusion

Fungizone Indication

Used to treat potentially life threatening fungal infections.

Fungizone Pharmacology

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

Fungizone Absorption

Bioavailability is 100% for intravenous infusion.

Fungizone side effects and Toxicity

Oral, rat: LD₅₀ = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

Fungizone Patient Information