Fungilin

Fungilin Brand names, Fungilin Analogs

Fungilin Brand Names Mixture

No information avaliable

Fungilin Chemical_Formula

C₄₇H₇₃NO₁₇

Fungilin RX_link

http://www.rxlist.com/cgi/generic2/amphoter.htm

Fungilin fda sheet

Fungilin FDA

Fungilin msds (material safety sheet)

Fungilin MSDS

Fungilin Synthesis Reference

No information avaliable

Fungilin Molecular Weight

924.079 g/mol

Fungilin Melting Point

170.0 ^oC

Fungilin H₂O Solubility

750 mg/L

Fungilin State

Solid

Fungilin LogP

0.947

Fungilin Dosage Forms

Slow intravenous-infusion

Fungilin Indication

Used to treat potentially life threatening fungal infections.

Fungilin Pharmacology

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

Fungilin Absorption

Bioavailability is 100% for intravenous infusion.

Fungilin side effects and Toxicity

Oral, rat: LD₅₀ = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

Fungilin Patient Information