Halizon
Halizon Brand names, Halizon Analogs
Halizon Brand Names Mixture
- No information avaliable
Halizon Chemical_Formula
C47H73NO17
Halizon RX_link
http://www.rxlist.com/cgi/generic2/amphoter.htm
Halizon fda sheet
Halizon msds (material safety sheet)
Halizon Synthesis Reference
No information avaliable
Halizon Molecular Weight
924.079 g/mol
Halizon Melting Point
170.0 oC
Halizon H2O Solubility
750 mg/L
Halizon State
Solid
Halizon LogP
0.947
Halizon Dosage Forms
Slow intravenous-infusion
Halizon Indication
Used to treat potentially life threatening fungal infections.
Halizon Pharmacology
Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.
Halizon Absorption
Bioavailability is 100% for intravenous infusion.
Halizon side effects and Toxicity
Oral, rat: LD50 = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.
Halizon Patient Information
No information avaliable
Halizon Organisms Affected
Various Fungus Species
