Amphozone

Amphozone Brand names, Amphozone Analogs

Amphozone Brand Names Mixture

No information avaliable

Amphozone Chemical_Formula

C₄₇H₇₃NO₁₇

Amphozone RX_link

http://www.rxlist.com/cgi/generic2/amphoter.htm

Amphozone fda sheet

Amphozone FDA

Amphozone msds (material safety sheet)

Amphozone MSDS

Amphozone Synthesis Reference

No information avaliable

Amphozone Molecular Weight

924.079 g/mol

Amphozone Melting Point

170.0 ^oC

Amphozone H₂O Solubility

750 mg/L

Amphozone State

Solid

Amphozone LogP

0.947

Amphozone Dosage Forms

Slow intravenous-infusion

Amphozone Indication

Used to treat potentially life threatening fungal infections.

Amphozone Pharmacology

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

Amphozone Absorption

Bioavailability is 100% for intravenous infusion.

Amphozone side effects and Toxicity

Oral, rat: LD₅₀ = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

Amphozone Patient Information