Mysteclin-F

Mysteclin-F Brand names, Mysteclin-F Analogs

Mysteclin-F Brand Names Mixture

No information avaliable

Mysteclin-F Chemical_Formula

C₄₇H₇₃NO₁₇

Mysteclin-F RX_link

http://www.rxlist.com/cgi/generic2/amphoter.htm

Mysteclin-F fda sheet

Mysteclin-F FDA

Mysteclin-F msds (material safety sheet)

Mysteclin-F MSDS

Mysteclin-F Synthesis Reference

No information avaliable

Mysteclin-F Molecular Weight

924.079 g/mol

Mysteclin-F Melting Point

170.0 ^oC

Mysteclin-F H₂O Solubility

750 mg/L

Mysteclin-F State

Solid

Mysteclin-F LogP

0.947

Mysteclin-F Dosage Forms

Slow intravenous-infusion

Mysteclin-F Indication

Used to treat potentially life threatening fungal infections.

Mysteclin-F Pharmacology

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

Mysteclin-F Absorption

Bioavailability is 100% for intravenous infusion.

Mysteclin-F side effects and Toxicity

Oral, rat: LD₅₀ = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

Mysteclin-F Patient Information