Fungisone

Fungisone Brand names, Fungisone Analogs

Fungisone Brand Names Mixture

No information avaliable

Fungisone Chemical_Formula

C₄₇H₇₃NO₁₇

Fungisone RX_link

http://www.rxlist.com/cgi/generic2/amphoter.htm

Fungisone fda sheet

Fungisone FDA

Fungisone msds (material safety sheet)

Fungisone MSDS

Fungisone Synthesis Reference

No information avaliable

Fungisone Molecular Weight

924.079 g/mol

Fungisone Melting Point

170.0 ^oC

Fungisone H₂O Solubility

750 mg/L

Fungisone State

Solid

Fungisone LogP

0.947

Fungisone Dosage Forms

Slow intravenous-infusion

Fungisone Indication

Used to treat potentially life threatening fungal infections.

Fungisone Pharmacology

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

Fungisone Absorption

Bioavailability is 100% for intravenous infusion.

Fungisone side effects and Toxicity

Oral, rat: LD₅₀ = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

Fungisone Patient Information