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Sombutol Brand names, Sombutol Analogs

Sombutol Brand Names Mixture

  • No information avaliable

Sombutol Chemical_Formula


Sombutol RX_link

No information avaliable

Sombutol fda sheet

Sombutol msds (material safety sheet)

Sombutol MSDS

Sombutol Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Sombutol Molecular Weight

232.235 g/mol

Sombutol Melting Point

174 oC

Sombutol H2O Solubility

<0.01 g/100 mL

Sombutol State


Sombutol LogP


Sombutol Dosage Forms

Tablet; Elixir

Sombutol Indication

For the treatment of Epilepsy

Sombutol Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Sombutol Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Sombutol side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Sombutol Patient Information


Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS

Sombutol Organisms Affected

Humans and other mammals