PharmacyCodes



Phenobarbituric Acid en es it fr

Phenobarbituric Acid Brand names, Phenobarbituric Acid Analogs

Phenobarbituric Acid Brand Names Mixture

  • No information avaliable

Phenobarbituric Acid Chemical_Formula

C12H12N2O3

Phenobarbituric Acid RX_link

No information avaliable

Phenobarbituric Acid fda sheet

Phenobarbituric Acid msds (material safety sheet)

Phenobarbituric_Acid MSDS

Phenobarbituric Acid Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Phenobarbituric Acid Molecular Weight

232.235 g/mol

Phenobarbituric Acid Melting Point

174 oC

Phenobarbituric Acid H2O Solubility

<0.01 g/100 mL

Phenobarbituric Acid State

Solid

Phenobarbituric Acid LogP

1.777

Phenobarbituric Acid Dosage Forms

Tablet; Elixir

Phenobarbituric Acid Indication

For the treatment of Epilepsy

Phenobarbituric Acid Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Phenobarbituric Acid Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Phenobarbituric Acid side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Phenobarbituric Acid Patient Information

PATIENT INFORMATION

Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS
depressant

Phenobarbituric Acid Organisms Affected

Humans and other mammals