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Lefebar Brand names, Lefebar Analogs

Lefebar Brand Names Mixture

  • No information avaliable

Lefebar Chemical_Formula


Lefebar RX_link

No information avaliable

Lefebar fda sheet

Lefebar msds (material safety sheet)

Lefebar MSDS

Lefebar Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Lefebar Molecular Weight

232.235 g/mol

Lefebar Melting Point

174 oC

Lefebar H2O Solubility

<0.01 g/100 mL

Lefebar State


Lefebar LogP


Lefebar Dosage Forms

Tablet; Elixir

Lefebar Indication

For the treatment of Epilepsy

Lefebar Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Lefebar Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Lefebar side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Lefebar Patient Information


Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS

Lefebar Organisms Affected

Humans and other mammals