Luminal

Luminal Brand names, Luminal Analogs

Luminal Brand Names Mixture

No information avaliable

Luminal Chemical_Formula

C₁₂H₁₂N₂O₃

Luminal RX_link

No information avaliable

Luminal fda sheet

Luminal msds (material safety sheet)

Luminal MSDS

Luminal Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Luminal Molecular Weight

232.235 g/mol

Luminal Melting Point

174 ^oC

Luminal H₂O Solubility

<0.01 g/100 mL

Luminal State

Solid

Luminal LogP

1.777

Luminal Dosage Forms

Tablet; Elixir

Luminal Indication

For the treatment of Epilepsy

Luminal Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Luminal Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Luminal side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Luminal Patient Information

PATIENT INFORMATION

Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS
depressant

Luminal Organisms Affected

Humans and other mammals