Agrypnal en es it fr

Agrypnal Brand names, Agrypnal Analogs

Agrypnal Brand Names Mixture

  • No information avaliable

Agrypnal Chemical_Formula


Agrypnal RX_link

No information avaliable

Agrypnal fda sheet

Agrypnal msds (material safety sheet)

Agrypnal MSDS

Agrypnal Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Agrypnal Molecular Weight

232.235 g/mol

Agrypnal Melting Point

174 oC

Agrypnal H2O Solubility

<0.01 g/100 mL

Agrypnal State


Agrypnal LogP


Agrypnal Dosage Forms

Tablet; Elixir

Agrypnal Indication

For the treatment of Epilepsy

Agrypnal Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Agrypnal Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Agrypnal side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Agrypnal Patient Information


Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS

Agrypnal Organisms Affected

Humans and other mammals