Barbiphenyl en es it fr

Barbiphenyl Brand names, Barbiphenyl Analogs

Barbiphenyl Brand Names Mixture

  • No information avaliable

Barbiphenyl Chemical_Formula

C12H12N2O3

Barbiphenyl RX_link

No information avaliable

Barbiphenyl fda sheet

Barbiphenyl msds (material safety sheet)

Barbiphenyl MSDS

Barbiphenyl Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Barbiphenyl Molecular Weight

232.235 g/mol

Barbiphenyl Melting Point

174 oC

Barbiphenyl H2O Solubility

<0.01 g/100 mL

Barbiphenyl State

Solid

Barbiphenyl LogP

1.777

Barbiphenyl Dosage Forms

Tablet; Elixir

Barbiphenyl Indication

For the treatment of Epilepsy

Barbiphenyl Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Barbiphenyl Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Barbiphenyl side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Barbiphenyl Patient Information

PATIENT INFORMATION

Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS
depressant

Barbiphenyl Organisms Affected

Humans and other mammals