Ensobarb en es it fr

Ensobarb Brand names, Ensobarb Analogs

Ensobarb Brand Names Mixture

  • No information avaliable

Ensobarb Chemical_Formula

C12H12N2O3

Ensobarb RX_link

No information avaliable

Ensobarb fda sheet

Ensobarb msds (material safety sheet)

Ensobarb MSDS

Ensobarb Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Ensobarb Molecular Weight

232.235 g/mol

Ensobarb Melting Point

174 oC

Ensobarb H2O Solubility

<0.01 g/100 mL

Ensobarb State

Solid

Ensobarb LogP

1.777

Ensobarb Dosage Forms

Tablet; Elixir

Ensobarb Indication

For the treatment of Epilepsy

Ensobarb Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Ensobarb Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Ensobarb side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Ensobarb Patient Information

PATIENT INFORMATION

Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS
depressant

Ensobarb Organisms Affected

Humans and other mammals