SK-Phenobarbital en es it fr

SK-Phenobarbital Brand names, SK-Phenobarbital Analogs

SK-Phenobarbital Brand Names Mixture

  • No information avaliable

SK-Phenobarbital Chemical_Formula

C12H12N2O3

SK-Phenobarbital RX_link

No information avaliable

SK-Phenobarbital fda sheet

SK-Phenobarbital msds (material safety sheet)

SK-Phenobarbital MSDS

SK-Phenobarbital Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

SK-Phenobarbital Molecular Weight

232.235 g/mol

SK-Phenobarbital Melting Point

174 oC

SK-Phenobarbital H2O Solubility

<0.01 g/100 mL

SK-Phenobarbital State

Solid

SK-Phenobarbital LogP

1.777

SK-Phenobarbital Dosage Forms

Tablet; Elixir

SK-Phenobarbital Indication

For the treatment of Epilepsy

SK-Phenobarbital Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

SK-Phenobarbital Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

SK-Phenobarbital side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

SK-Phenobarbital Patient Information

PATIENT INFORMATION

Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS
depressant

SK-Phenobarbital Organisms Affected

Humans and other mammals