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Amylofene Brand names, Amylofene Analogs

Amylofene Brand Names Mixture

  • No information avaliable

Amylofene Chemical_Formula

C12H12N2O3

Amylofene RX_link

No information avaliable

Amylofene fda sheet

Amylofene msds (material safety sheet)

Amylofene MSDS

Amylofene Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Amylofene Molecular Weight

232.235 g/mol

Amylofene Melting Point

174 oC

Amylofene H2O Solubility

<0.01 g/100 mL

Amylofene State

Solid

Amylofene LogP

1.777

Amylofene Dosage Forms

Tablet; Elixir

Amylofene Indication

For the treatment of Epilepsy

Amylofene Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Amylofene Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Amylofene side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Amylofene Patient Information

PATIENT INFORMATION

Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS
depressant

Amylofene Organisms Affected

Humans and other mammals