Barbonal

Barbonal Brand names, Barbonal Analogs

Barbonal Brand Names Mixture

No information avaliable

Barbonal Chemical_Formula

C₁₂H₁₂N₂O₃

Barbonal RX_link

No information avaliable

Barbonal fda sheet

Barbonal msds (material safety sheet)

Barbonal MSDS

Barbonal Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Barbonal Molecular Weight

232.235 g/mol

Barbonal Melting Point

174 ^oC

Barbonal H₂O Solubility

<0.01 g/100 mL

Barbonal State

Solid

Barbonal LogP

1.777

Barbonal Dosage Forms

Tablet; Elixir

Barbonal Indication

For the treatment of Epilepsy

Barbonal Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Barbonal Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Barbonal side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Barbonal Patient Information

PATIENT INFORMATION

Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS
depressant

Barbonal Organisms Affected

Humans and other mammals