Phenoluric en es it fr

Phenoluric Brand names, Phenoluric Analogs

Phenoluric Brand Names Mixture

  • No information avaliable

Phenoluric Chemical_Formula

C12H12N2O3

Phenoluric RX_link

No information avaliable

Phenoluric fda sheet

Phenoluric msds (material safety sheet)

Phenoluric MSDS

Phenoluric Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Phenoluric Molecular Weight

232.235 g/mol

Phenoluric Melting Point

174 oC

Phenoluric H2O Solubility

<0.01 g/100 mL

Phenoluric State

Solid

Phenoluric LogP

1.777

Phenoluric Dosage Forms

Tablet; Elixir

Phenoluric Indication

For the treatment of Epilepsy

Phenoluric Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Phenoluric Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Phenoluric side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Phenoluric Patient Information

PATIENT INFORMATION

Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS
depressant

Phenoluric Organisms Affected

Humans and other mammals