Lepinal

Lepinal Brand names, Lepinal Analogs

Lepinal Brand Names Mixture

No information avaliable

Lepinal Chemical_Formula

C₁₂H₁₂N₂O₃

Lepinal RX_link

No information avaliable

Lepinal fda sheet

Lepinal msds (material safety sheet)

Lepinal MSDS

Lepinal Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Lepinal Molecular Weight

232.235 g/mol

Lepinal Melting Point

174 ^oC

Lepinal H₂O Solubility

<0.01 g/100 mL

Lepinal State

Solid

Lepinal LogP

1.777

Lepinal Dosage Forms

Tablet; Elixir

Lepinal Indication

For the treatment of Epilepsy

Lepinal Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Lepinal Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Lepinal side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Lepinal Patient Information

PATIENT INFORMATION

Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS
depressant

Lepinal Organisms Affected

Humans and other mammals