Phenobarbyl en es it fr

Phenobarbyl Brand names, Phenobarbyl Analogs

Phenobarbyl Brand Names Mixture

  • No information avaliable

Phenobarbyl Chemical_Formula


Phenobarbyl RX_link

No information avaliable

Phenobarbyl fda sheet

Phenobarbyl msds (material safety sheet)

Phenobarbyl MSDS

Phenobarbyl Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Phenobarbyl Molecular Weight

232.235 g/mol

Phenobarbyl Melting Point

174 oC

Phenobarbyl H2O Solubility

<0.01 g/100 mL

Phenobarbyl State


Phenobarbyl LogP


Phenobarbyl Dosage Forms

Tablet; Elixir

Phenobarbyl Indication

For the treatment of Epilepsy

Phenobarbyl Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Phenobarbyl Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Phenobarbyl side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Phenobarbyl Patient Information


Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS

Phenobarbyl Organisms Affected

Humans and other mammals