Promazine
Promazine Brand names, Promazine Analogs
- AB
- Aminazin
- Aminazine
- Ampazine
- Ampliactil
- Amplictil
- Berophen
- CPZ
- Chlor-Promanyl
- Chlordelazin
- Chlorderazin
- Chlorpromados
- Chlorpromazine Hcl
- Chlorpromazine Hcl Intensol
- Chlropromados
- Contomin
- Elmarin
- Esmind
- Esparin
- Fenactil
- Fenaktyl
- Fraction
- Largactil
- Largactilothiazine
- Largactyl
- Liranol
- Megaphen
- Neo-Hibernex
- Novomazina
- Phenactyl
- Phenothiazine
- Prazin
- Prazine
- Proma
- Promactil
- Promapar
- Promazil
- Promazin
- Promazina
- Promazine Hcl
- Promwill
- Propaphenin
- Protactyl
- Prozil
- Psychozine
- Romtiazin
- Sanopron
- Sinophenin
- Sonazine
- Sparine
- Thorazine
- Tomil
- Torazina
- Verophen
- Vesprin
- Wintermin
Promazine Brand Names Mixture
- No information avaliable
Promazine Chemical_Formula
C17H20N2S
Promazine RX_link
No information avaliable
Promazine fda sheet
Promazine msds (material safety sheet)
Promazine Synthesis Reference
No information avaliable
Promazine Molecular Weight
284.42 g/mol
Promazine Melting Point
< 25 oC
Promazine H2O Solubility
14.2 mg/L
Promazine State
Liquid
Promazine LogP
4.893
Promazine Dosage Forms
Tablet; Oral liquid; Injection
Promazine Indication
Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly.
Promazine Pharmacology
Promazine belongs to a group of medications known as the phenothiazine antipsychotics. It acts by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is involved in transmitting signals between brain cells. When there is an excess amount of dopamine in the brain it causes over-stimulation of dopamine receptors. These receptors normally act to modify behaviour and over-stimulation may result in psychotic illness. Promazine hydrochloride blocks these receptors and stops them becoming over-stimulated, thereby helping to control psychotic illness. Promazine has weak extrapyramidal and autonomic side effects which lead to its use in the elderly, for restless or psychotic patients. Its anti-psychotic effect is also weaker and it is not useful in general psychiatry.
Promazine Absorption
Absorption may be erratic and peak plasma concentrations show large interindividual differences.
Promazine side effects and Toxicity
Side effects include: extrapyramidal symptoms, drowsiness, weight gain, dry mouth, constipation, endocrine effects (such as gynaecomastia and menstrual disturbance), sensitivity to sunlight and haemolytic anaemia.
Promazine Patient Information
No information avaliable
Promazine Organisms Affected
Humans and other mammals
