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Esparin Brand names, Esparin Analogs

Esparin Brand Names Mixture

  • No information avaliable

Esparin Chemical_Formula


Esparin RX_link

No information avaliable

Esparin fda sheet

Esparin msds (material safety sheet)

Esparin Synthesis Reference

No information avaliable

Esparin Molecular Weight

284.42 g/mol

Esparin Melting Point

< 25 oC

Esparin H2O Solubility

14.2 mg/L

Esparin State


Esparin LogP


Esparin Dosage Forms

Tablet; Oral liquid; Injection

Esparin Indication

Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly.

Esparin Pharmacology

Promazine belongs to a group of medications known as the phenothiazine antipsychotics. It acts by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is involved in transmitting signals between brain cells. When there is an excess amount of dopamine in the brain it causes over-stimulation of dopamine receptors. These receptors normally act to modify behaviour and over-stimulation may result in psychotic illness. Promazine hydrochloride blocks these receptors and stops them becoming over-stimulated, thereby helping to control psychotic illness. Promazine has weak extrapyramidal and autonomic side effects which lead to its use in the elderly, for restless or psychotic patients. Its anti-psychotic effect is also weaker and it is not useful in general psychiatry.

Esparin Absorption

Absorption may be erratic and peak plasma concentrations show large interindividual differences.

Esparin side effects and Toxicity

Side effects include: extrapyramidal symptoms, drowsiness, weight gain, dry mouth, constipation, endocrine effects (such as gynaecomastia and menstrual disturbance), sensitivity to sunlight and haemolytic anaemia.

Esparin Patient Information

No information avaliable

Esparin Organisms Affected

Humans and other mammals