Promazine Hcl en es it fr

Promazine Hcl Brand names, Promazine Hcl Analogs

Promazine Hcl Brand Names Mixture

  • No information avaliable

Promazine Hcl Chemical_Formula


Promazine Hcl RX_link

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Promazine Hcl fda sheet

Promazine Hcl msds (material safety sheet)

Promazine Hcl Synthesis Reference

No information avaliable

Promazine Hcl Molecular Weight

284.42 g/mol

Promazine Hcl Melting Point

< 25 oC

Promazine Hcl H2O Solubility

14.2 mg/L

Promazine Hcl State


Promazine Hcl LogP


Promazine Hcl Dosage Forms

Tablet; Oral liquid; Injection

Promazine Hcl Indication

Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly.

Promazine Hcl Pharmacology

Promazine belongs to a group of medications known as the phenothiazine antipsychotics. It acts by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is involved in transmitting signals between brain cells. When there is an excess amount of dopamine in the brain it causes over-stimulation of dopamine receptors. These receptors normally act to modify behaviour and over-stimulation may result in psychotic illness. Promazine hydrochloride blocks these receptors and stops them becoming over-stimulated, thereby helping to control psychotic illness. Promazine has weak extrapyramidal and autonomic side effects which lead to its use in the elderly, for restless or psychotic patients. Its anti-psychotic effect is also weaker and it is not useful in general psychiatry.

Promazine Hcl Absorption

Absorption may be erratic and peak plasma concentrations show large interindividual differences.

Promazine Hcl side effects and Toxicity

Side effects include: extrapyramidal symptoms, drowsiness, weight gain, dry mouth, constipation, endocrine effects (such as gynaecomastia and menstrual disturbance), sensitivity to sunlight and haemolytic anaemia.

Promazine Hcl Patient Information

No information avaliable

Promazine Hcl Organisms Affected

Humans and other mammals