Promazin
Promazin Brand names, Promazin Analogs
- AB
- Aminazin
- Aminazine
- Ampazine
- Ampliactil
- Amplictil
- Berophen
- CPZ
- Chlor-Promanyl
- Chlordelazin
- Chlorderazin
- Chlorpromados
- Chlorpromazine Hcl
- Chlorpromazine Hcl Intensol
- Chlropromados
- Contomin
- Elmarin
- Esmind
- Esparin
- Fenactil
- Fenaktyl
- Fraction
- Largactil
- Largactilothiazine
- Largactyl
- Liranol
- Megaphen
- Neo-Hibernex
- Novomazina
- Phenactyl
- Phenothiazine
- Prazin
- Prazine
- Proma
- Promactil
- Promapar
- Promazil
- Promazin
- Promazina
- Promazine Hcl
- Promwill
- Propaphenin
- Protactyl
- Prozil
- Psychozine
- Romtiazin
- Sanopron
- Sinophenin
- Sonazine
- Sparine
- Thorazine
- Tomil
- Torazina
- Verophen
- Vesprin
- Wintermin
Promazin Brand Names Mixture
- No information avaliable
Promazin Chemical_Formula
C17H20N2S
Promazin RX_link
No information avaliable
Promazin fda sheet
Promazin msds (material safety sheet)
Promazin Synthesis Reference
No information avaliable
Promazin Molecular Weight
284.42 g/mol
Promazin Melting Point
< 25 oC
Promazin H2O Solubility
14.2 mg/L
Promazin State
Liquid
Promazin LogP
4.893
Promazin Dosage Forms
Tablet; Oral liquid; Injection
Promazin Indication
Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly.
Promazin Pharmacology
Promazine belongs to a group of medications known as the phenothiazine antipsychotics. It acts by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is involved in transmitting signals between brain cells. When there is an excess amount of dopamine in the brain it causes over-stimulation of dopamine receptors. These receptors normally act to modify behaviour and over-stimulation may result in psychotic illness. Promazine hydrochloride blocks these receptors and stops them becoming over-stimulated, thereby helping to control psychotic illness. Promazine has weak extrapyramidal and autonomic side effects which lead to its use in the elderly, for restless or psychotic patients. Its anti-psychotic effect is also weaker and it is not useful in general psychiatry.
Promazin Absorption
Absorption may be erratic and peak plasma concentrations show large interindividual differences.
Promazin side effects and Toxicity
Side effects include: extrapyramidal symptoms, drowsiness, weight gain, dry mouth, constipation, endocrine effects (such as gynaecomastia and menstrual disturbance), sensitivity to sunlight and haemolytic anaemia.
Promazin Patient Information
No information avaliable
Promazin Organisms Affected
Humans and other mammals
