Chlor-Promanyl
Chlor-Promanyl Brand names, Chlor-Promanyl Analogs
- AB
- Aminazin
- Aminazine
- Ampazine
- Ampliactil
- Amplictil
- Berophen
- CPZ
- Chlor-Promanyl
- Chlordelazin
- Chlorderazin
- Chlorpromados
- Chlorpromazine Hcl
- Chlorpromazine Hcl Intensol
- Chlropromados
- Contomin
- Elmarin
- Esmind
- Esparin
- Fenactil
- Fenaktyl
- Fraction
- Largactil
- Largactilothiazine
- Largactyl
- Liranol
- Megaphen
- Neo-Hibernex
- Novomazina
- Phenactyl
- Phenothiazine
- Prazin
- Prazine
- Proma
- Promactil
- Promapar
- Promazil
- Promazin
- Promazina
- Promazine Hcl
- Promwill
- Propaphenin
- Protactyl
- Prozil
- Psychozine
- Romtiazin
- Sanopron
- Sinophenin
- Sonazine
- Sparine
- Thorazine
- Tomil
- Torazina
- Verophen
- Vesprin
- Wintermin
Chlor-Promanyl Brand Names Mixture
- No information avaliable
Chlor-Promanyl Chemical_Formula
C17H20N2S
Chlor-Promanyl RX_link
No information avaliable
Chlor-Promanyl fda sheet
Chlor-Promanyl msds (material safety sheet)
Chlor-Promanyl Synthesis Reference
No information avaliable
Chlor-Promanyl Molecular Weight
284.42 g/mol
Chlor-Promanyl Melting Point
< 25 oC
Chlor-Promanyl H2O Solubility
14.2 mg/L
Chlor-Promanyl State
Liquid
Chlor-Promanyl LogP
4.893
Chlor-Promanyl Dosage Forms
Tablet; Oral liquid; Injection
Chlor-Promanyl Indication
Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly.
Chlor-Promanyl Pharmacology
Promazine belongs to a group of medications known as the phenothiazine antipsychotics. It acts by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is involved in transmitting signals between brain cells. When there is an excess amount of dopamine in the brain it causes over-stimulation of dopamine receptors. These receptors normally act to modify behaviour and over-stimulation may result in psychotic illness. Promazine hydrochloride blocks these receptors and stops them becoming over-stimulated, thereby helping to control psychotic illness. Promazine has weak extrapyramidal and autonomic side effects which lead to its use in the elderly, for restless or psychotic patients. Its anti-psychotic effect is also weaker and it is not useful in general psychiatry.
Chlor-Promanyl Absorption
Absorption may be erratic and peak plasma concentrations show large interindividual differences.
Chlor-Promanyl side effects and Toxicity
Side effects include: extrapyramidal symptoms, drowsiness, weight gain, dry mouth, constipation, endocrine effects (such as gynaecomastia and menstrual disturbance), sensitivity to sunlight and haemolytic anaemia.
Chlor-Promanyl Patient Information
No information avaliable
Chlor-Promanyl Organisms Affected
Humans and other mammals
